Breast Cancer Foundation NZ
CheckMate 7A8
Early Breast Cancer clinical trials for ER+
A study of neoadjuvant nivolumab + palbociclib + anastrozole in post-menopausal women and men with primary breast cancer.
A study of neoadjuvant nivolumab + palbociclib + anastrozole in post-menopausal women and men with primary breast cancer.
Who is it for?
You may be eligible for this study if you meet the below criteria:
- Participants must have untreated, unilateral, histologically confirmed ER+, HER2- invasive breast cancer with primary tumor =2 cm in largest diameter (cT1-3) in one dimension by clinical or radiographic exam, for whom neoadjuvant endocrine monotherapy deemed to be a suitable therapy.
- Participants must be deemed eligible for surgery and must agree to undergo surgery after completion of neoadjuvant therapy and agree to provide tumor tissue at baseline, on-treatment, and at surgery.
- Women must have documented proof that they are not of childbearing potential.
- Participants must have a performance status (PS) = 1 on the Eastern Cooperative Oncology Group (ECOG) scale.
Study details
Patients will receive either (1) nivolumab + palbociclib + anastrozole (ANZ); (2) palbociclib + ANZ then nivolumab + palbociclib + ANZ; or (3) palbociclib + ANZ.
Australia
Breast Cancer Research Centre, Nedlands
If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.
Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz
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