PRiMo - Clinical trial • Breast Cancer Foundation NZ

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PRiMo

Recruiting
Updated: June 11, 2021

This trial is investigating the efficacy and feasibility of a personalised risk assessment for breast and ovarian cancer, through offering a polygenic risk score.

Who is it for?
You may be eligible for this trial if you are a woman aged 18 years and above undergoing a predictive test for a known familial mutation in a gene associated with increased risk of breast cancer - BRCA1, BRCA2, PALB2, CHEK2, ATM, RAD51C or RAD51D at a participating Familial Cancer Clinic. You may also be eligible if you have previously completed predictive testing that detected PALB2, CHEK2, ATM, RAD51C, or RAD51D at a participating Familial Cancer Clinic.

Study details

Participants will be randomly allocated to either the intervention arm, or a waitlist control that will be eligible to receive the personalised risk assessment after 1 year. The intervention arm will receive an integrated, personalised risk assessment and risk management advice, whereas the control arm will receive risk management advice based on the standard risk assessment incorporating the results of single gene testing and family cancer history.

Information from this trial will be used to optimise targeted risk management of breast and ovarian cancer, whilst minimising the burden and cost to the health system

Full trial information

Australia

Recruiting:
Peter MacCallum Cancer Centre, Melbourne
Royal Melbourne Hospital, Melbourne

Not yet recruiting:
The Royal Adelaide Hospital, Adelaide
Royal Brisbane & Women's Hospital, Brisbane
Royal Hobart Hospital, Hobart
Austin Hospital, Melbourne
Cabrini Hospital, Melbourne
Monash Medical Centre (Clayton), Melbourne
King Edward Memorial Hospital, Perth
Prince of Wales Hospital, Sydney
Royal Prince Alfred Hospital, Sydney
Royal North Shore Hospital, Sydney
Westmead Hospital, Sydney

Contact:

PRiMo trial co-ordinator

If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.

Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz

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Are we out of date? If you have updated or new information about a trial, we’d be grateful if you’d share it with us – email your update to intouch@bcf.org.nz

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