Breast Cancer Foundation NZ
LOLIPOP trial
The Lolipop trial (Long term Outcomes of Lidocaine Infusions for Post-Operative Pain) is looking at whether lidocaine infusions given during surgery and up to 24 hours after surgery, helps with moderate or severe chronic pain at one year following surgery for breast cancer.
This is a large, phase III trial that aims to recruit around 4,300 patients from the UK, Hong Kong, Australia and New Zealand.
What's involved?
Patients will be randomly allocated to one of two groups:
Group 1: Treatment group. Patients will be given lidocaine during anaesthesia as well as up to 24 hours after surgery.
Group 2: Placebo group. Patients will be given placebo during anaesthesia and 24 hours after surgery.
You won't know which group will will be in.
Who is it for?
Inclusion Criteria:
- Female aged 18 years or over
- undergoing mastectomy or breast conserving surgery for the removal of primary breast cancer under general anaesthesia
Exclusion Criteria:
- undergoing mastectomy or breast conserving surgery with add on procedures e.g laparoscopic salpingectomy
- surgery for locoregional recurrence of breast cancer
- Pre-existing pain at site of surgery, axilla, chest wall or the upper arm on the same side of tumour (at diagnosis prior to any tumor locating procedures)
- Re-excision procedures where the margins at the first surgery were not sufficient
There are also other exclusion criteria which might mean mean you will not be able to take part in this trial. Check with your study site to see if this trial is right for you.
New Zealand
Auckland City Hospital and Middlemore Hospital
Waikato Hospital
Australia
QLD
SA
TAS
VIC
WA
If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.
Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz
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Are we out of date? If you have updated or new information about a trial, we’d be grateful if you’d share it with us – email your update to intouch@bcf.org.nz
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