MK-2870-011/​TroFuse-011 - Clinical trial • Breast Cancer Foundation NZ

MK-2870-011/​TroFuse-011

Advanced Breast Cancer clinical trials for Triple negative

Recruiting
Updated: September 8, 2025

Researchers want to know if MK-2870 given by itself or with Keytruda (pembrolizumab) can treat triple negative breast cancer (TNBC). The main goal of this study is to learn if people treated with MK-2870 alone or with pembrolizumab live longer overall or without the cancer growing or spreading compared to people treated with chemotherapy.

This is a phase 3, randomized, open-label study comparing the efficacy and safety of MK-2870, given alone or in combination with Keytruda (pembrolizumab) versus treatment of physician's choice in patients with previously untreated locally recurrent (unable to be surgically removed) or metastatic triple-negative breast cancer expressing PD-L1 at CPS Less Than 10.

The drug, MK-2870, is also known as sacituzumab tirumotecan.

Criteria:

  • Patients aged 18 years or over 
  • Previously untreated locally recurrent (unable to be surgically removed) or metastatic triple-negative breast cancer 
  • PD-L1 at CPS < 10. 

Information about this trial can also be found on the website of Harbour Cancer and Wellness.

A qualified healthcare professional will help you to determine if you are eligible to take part in this clinical trial. This information may be useful in starting a conversation with your doctor.

New Zealand

Harbour Cancer and Wellness

If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.

Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz

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