BRCA-P - Clinical trial • Breast Cancer Foundation NZ

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Updated: January 30, 2020

BRCA-P is an international breast cancer prevention clinical trial open to women with a confirmed BRCA1 gene mutation who have not had a diagnosis of breast cancer.

The BRCA-P study will investigate if using Denosumab is a safe and effective way of preventing breast cancer.

Participants on BRCA-P will receive a study medication injection (Denosumab or placebo) every six months for five years. This study is a randomised, double-blind, placebo-controlled study, which means participants, and their study doctor, will not know if they are receiving the Denosumab or placebo (a treatment that looks just like the active medication, but has no effect).

If you are a woman between 25 and 55, with a known BRCA1 gene mutation, no current or previous breast cancer diagnosis, and not planning to have, or have not already completed surgery to remove both breasts, this trial might be suitable for you.

Full trial information


Royal Adelaide Hospital, Adelaide
Ballarat Oncology and Haematology Services, Ballarat
Royal Brisbane and Women's Hospital, Brisbane
Royal Hobart Hospital, Hobart
Lake Macquarie Private Hospital, Lake Macquarie
Austin Hospital, Melbourne
Monash Medical Centre (Clayton), Melbourne
The Royal Melbourne Hospital, Melbourne
St John of God Hospital, Subiaco
Concord Repatriation General Hospital, Sydney
Prince of Wales Hospital, Sydney
Royal North Shore Hospital, Sydney (not yet recruiting)
St Vincent's Hospital, Sydney
Westmead Hospital, Sydney
Wollongong Hospital, Wollongong


Geoff Lindeman

If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.

Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at

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