AVATAR - Clinical trial • Breast Cancer Foundation NZ

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Advanced Breast Cancer clinical trials for ER+

Updated: December 7, 2020

This study will investigate the effect of stereotactic radiotherapy to see whether it helps women with ER+, HER2- advanced breast cancer continue CDK 4/6 treatment for longer.

This study will investigate the safety and efficacy of stereotactic radiotherapy treatment in combination with aromatase inhibitor and CDK4/6 inhibitor for advanced breast cancer. This research will give researchers information about whether adding radiotherapy to a CDK4/6 inhibitor increases the amount of time participants can stay on CDK4/6 inhibitor therapy.

Who is it for?

You may be eligible to join this study if you are aged 18 and above, have histologically proven ER+, HER2-advanced breast cancer with metastases and receiving an aromatase inhibitor in combination with a CDK 4/6 inhibitor.

Study details

All participants in this study receive stereotactic radiotherapy (between one to five doses as ascertained by treating doctor after consultation) in combination with prescribed aromatase inhibitor and CDK 4/6 inhibitor.

Participants will be monitored for reactions and treatment effectiveness, and provide blood and urine for analysis throughout the two-year study.

Full trial information


Genesis Cancer Care, Brisbane
The Canberra Hospital, Canberra
Monash Medical Centre, Melbourne
Peter MacCullum Cancer Centre, Melbourne
St Vincent's Hospital, Melbourne
The Townsville Hospital, Townsville


Suzie Roache

If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.

Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz

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For Advanced Breast Cancer

Are we out of date? If you have updated or new information about a trial, we’d be grateful if you’d share it with us – email your update to intouch@bcf.org.nz

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