This study will investigate the safety and efficacy of stereotactic radiotherapy treatment in combination with aromatase inhibitor and CDK4/6 inhibitor for advanced breast cancer. This research will give researchers information about whether adding radiotherapy to a CDK4/6 inhibitor increases the amount of time participants can stay on CDK4/6 inhibitor therapy.
Who is it for?
You may be eligible to join this study if you are aged 18 and above, have histologically proven ER+, HER2-advanced breast cancer with metastases and receiving an aromatase inhibitor in combination with a CDK 4/6 inhibitor.
Study details
All participants in this study receive stereotactic radiotherapy (between one to five doses as ascertained by treating doctor after consultation) in combination with prescribed aromatase inhibitor and CDK 4/6 inhibitor.
Participants will be monitored for reactions and treatment effectiveness, and provide blood and urine for analysis throughout the two-year study.
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