Breast Cancer Foundation NZ
ELIMINATE
Advanced Breast Cancer clinical trials for ER+
The purpose of this phase II trial is to test whether giving two types of breast cancer treatment (chemotherapy and hormone treatment) at the same time is more effective than giving them one after the other (which is usually done).
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This trial will be conducted in women with breast cancer that is large and/or attached to nearby tissues, for whom shrinkage of tumour using neoadjuvant therapy before surgery could mean the operation is easier and a smaller operation than mastectomy may be possible. Women with metastatic breast cancer are excluded. The current standard for women with larger ER positive breast cancer is preoperative chemotherapy alone, followed by surgery, then adjuvant endocrine therapy. Endocrine therapy is regarded as the mainstay of adjuvant treatment for women with receptor positive breast cancer, and neoadjuvant chemotherapy rarely results in complete disappearance of cancer by the time of surgery. The purpose of this trial is to examine whether combining chemotherapy and endocrine therapy is more effective than chemotherapy alone at downstaging receptor positive breast cancer before surgery. All participants will receive active treatment with neoadjuvant chemotherapy, with or without letrozole (and goserelin for pre/peri menopausal women). |
New Zealand
If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.
Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz
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For Advanced Breast Cancer
Are we out of date? If you have updated or new information about a trial, we’d be grateful if you’d share it with us – email your update to intouch@bcf.org.nz
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