EMBRACE - Clinical trial • Breast Cancer Foundation NZ

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Advanced Breast Cancer clinical trials for Triple negative

Updated: August 9, 2021

This study is testing olaparib, in homologous recombination (HR) deficient metastatic breast cancer in patients who do not have hereditary mutations in BRCA1 and BRCA2.

This study is testing olaparib, in Homologous recombination (HR) deficient metastatic breast and relapsed ovarian cancer in patients who do not have hereditary mutations in BReast CAncer susceptibility gene 1 and gene 2 (BRCA1 and BRCA2).

Who is it for?

You may be eligible to join this study if you are aged 18 years or above and are either: a) men or women with confirmed evidence of metastatic triple negative breast cancer.

Study details

All study participants will take olaparib 300mg orally twice daily until disease progression or unacceptable toxicity. Assessments for safety and efficacy will be followed up for a minimum of six months.

Olaparib, has been approved overseas and in Australia in women shown to have inherited changes in their BRCA1 or 2 genes. There is strong evidence to show that olaparib will also work in people who do not have any changes in their genes. The purpose of this study is to assess whether the olaparib is effective in treating these tumours.

Full trial information


Ballarat Oncology and Haematology Services, Adelaide
The Royal Adelaide Hospital, Adelaide
Border Medical Oncology, Albury
Icon Cancer Care Wesley, Brisbane
Royal Brisbane & Womens Hospital, Brisbane
Coffs Harbour Base Hospital, Coffs Harbour
Pindara Private Hospital, Gold Coast
Peter MacCallum Cancer Centre, Melbourne
Fiona Stanley Hospital, Perth
Royal North Shore Hospital, Sydney
St George Hospital, Sydney


Trial Co-ordinator

If you think you might be a candidate for this trial, use the contact details supplied, or talk to your doctor.

Want to access a trial that's not in your area? It's not always possible, but if you're interested, email us at intouch@bcf.org.nz

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For Advanced Breast Cancer

Are we out of date? If you have updated or new information about a trial, we’d be grateful if you’d share it with us – email your update to intouch@bcf.org.nz

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